Ozempic is STILL less effective at burning fat and way more expensive in the long run than weight loss surgery, study finds

They person been hyped up arsenic an antidote to America's obesity situation - but weight loss narcotics for illustration Ozempic are still much costly and little effective than plain aged surgery.

The injections were recovered to costs doubly arsenic overmuch and lead to astir 4 percent little weight nonaccomplishment compared to an cognition that's been astir for years.

Researchers from Brigham and Women's Hospital successful Boston recovered that weight-loss narcotics containing semaglutide costs much than $53,000 complete 5 years, compared to a 'stomach stich'  which came to little than $20,000. 

The operation, wherever portion of nan tummy is stitched up to make it smaller, was besides recovered to beryllium much effective astatine sustaining nan astir weight nonaccomplishment aft 5 years - people's BMI aft nan weight-loss room was 31.7 compared to 33.0.

Researchers said nan value of Ozempic and akin narcotics would request to beryllium reduced three-fold, from $13,618 to $3,591, for it to beryllium nan preferred option.

Semaglutide has go celebrated owed to its noninvasiveness, easiness of usage arsenic a play injection, and short-term effectiveness, nan researchers said. 

An endoscopic sleeve gastroplasty (ESG), connected nan different hand, is simply a one-time process that tin beryllium repeated a fewer years later, if nan tummy has stretched aliases stitches person loosened.

ESG is simply a minimally invasive weight-loss process which reduces nan size of nan tummy without nan request for an incision done nan skin.

TV personage Stacey Silva had nan process and reality prima Alana "Honey Boo Boo" Thompson is besides owed to acquisition nan surgery.

The study compared ESG pinch semaglutide to dainty patients pinch people 2 obesity, which intends they had a BMI of 35-39.9, complete 5 years. 

The guidelines lawsuit they looked astatine was a 45-year-old diligent pinch a BMI of 37. They past utilized publically disposable information from objective tests to simulate different hypothetical patients.

The researchers simulated 2 curen strategies - semaglutide and ESG - versus nary treatment.

An ESG is done utilizing a elastic conduit passed down done nan pharynx pinch a camera attached, and past a surgeon closes disconnected a information of nan tummy pinch stitches.

This reduces nan size which restricts really overmuch personification tin eat.

The exemplary incorporated costs of ESG, repetition ESG and nan costs of treating imaginable adverse events aft nan surgery, which could temporary stomachache, nausea and vomiting.

As pinch immoderate type of surgery, location are besides very mini risks of superior complications from nan cognition itself. These tin see bleeding, infection and tears successful nan stomach. 

A meta-analysis of studies recovered that complaint of adverse effects ranged from 1.5 percent to 2.3 percent. 

For Ozempic, researchers calculated nan monthly costs of semaglutide, which is astir $1,000 a month.

An endoscopic sleeve gastroplasty usually costs betwixt $7,000 and $9,000, according to Bagshahi Bariatric and General Surgery successful Texas. Health security whitethorn screen portion of nan costs if nan personification is clinically obese.

Semaglutide is simply a once-weekly injection that useful by delaying nan emptying of nan stomach, which leads to patients emotion fuller for longer and a decreased wide appetite.

The shots tin trigger a assortment of nasty broadside effects. Users commonly kick of nausea, vomiting, constipation and diarrhea. 

In 1 study, immoderate 15.8 percent of patients utilizing Ozempic suffered nausea, 7.3 percent abdominal symptom and 8.5 percent diarrhea. 

In much superior cases, nan supplier has been shown to summation nan consequence of a paralyzed stomach, pancreatitis and bowel blockages. 

Patients request to enactment connected nan medicine for life, and arsenic they tin regain immoderate weight nonaccomplishment if they extremity taking it.

The study was published successful nan diary JAMA Network.