Be warned of the 'Ozempic wall'! Experts say little-known issue will affect EVERYONE on miracle slimming jabs - and it can kick in after just six weeks

Wannabe slimmers were coming warned astir a little-known rumor pinch weight nonaccomplishment jabs that will impact anyone taking them. 

Game-changing injections specified arsenic Ozempic and Wegovy, hailed by nan likes of Elon Musk and Jeremy Clarkson, are proven to thief group suffer up to 2st. 

But experts said that anyone relying connected them to combat agelong word weight nonaccomplishment could beryllium near disappointed, pinch nan effects of nan narcotics halting aft conscionable months. 

Some users person deed nan alleged 'Ozempic wall' aft conscionable six weeks, complaining connected online forums astir really they're now struggling to displacement nan pounds contempt fasting and exercising.  

Professor Naveed Sattar, an master successful cardiometabolic medicine astatine nan University of Glasgow, told MailOnline: 'As lighter group pain little calories, weight will ever plateau complete time, arsenic pinch immoderate weight nonaccomplishment intervention.

'The magnitude of calories consumed will yet equilibrium pinch little calories burned to lead to a caller dependable weight.'

Semaglutide, however, does still 'work good successful astir people', he added. 

The pens, taken erstwhile a day, instrumentality nan encephalon and make nan assemblage deliberation it is full, curbing appetite. 

Effects tin beryllium visible wrong weeks. 

Patients connected them declare to person been near repulsed by their favourite foods, including coffee, cocoa and fried chicken.

But tests show users of semaglutide – nan powerful constituent successful some Ozempic and Wegovy — tin put weight backmost connected arsenic soon arsenic they extremity taking it. 

According to 1 2022 study by researchers astatine Aintree University Hospital, erstwhile a diligent drops retired of nan regimen, astir of their weight returns, on pinch related risks for bosom illness and type 2 diabetes.

These see obesity, chronic body-wide inflammation and problems pinch insulin control.

The researchers studied astir 1,900 group who had received glucagon-like peptide-1 hormone (GLP-1) injections for much than a twelvemonth and recovered that 12 months aft they stopped nan therapy, they had regained connected mean two-thirds of immoderate weight they'd mislaid while connected nan drug. 

Appearing on the Tonight Show Starring Jimmy Fallon earlier this month, 55-year-old American comedian and character Tracy Morgan revealed he yet 'out-ate' Ozempic and gained 40 pounds (18kg) while taking it. 

Last year, TikTok prima Remi Bader admitted that stopping Ozempic made her binge eating get 'so overmuch worse'.

She said she was prescribed it because she was pre-diabetic and insulin-resistant and gaining weight.

'They said I request this. And I had a batch of mixed feelings,' she said. 'Because past ... a fewer months later, sewage into nan bad bingeing and went disconnected it.'

She added: 'I saw a doctor, and they were like, "It's 100 per cent because you went connected Ozempic". 

Ahmed Ahmed, a advisor bariatric surgeon astatine Imperial College Healthcare NHS Trust successful London, said: 'Unrealistic expectations of a weight-loss cure person been driven by societal media, not subject aliases medicine, and by trading alternatively than nationalist health.

'This has created immoderate superior misconceptions: these narcotics tin surely work, but objective tests show that astir a 3rd of group don't respond to GLP-1 drugs.

'People besides deliberation that they will extremity up astatine their perfect weight, but astir conscionable don't suffer that much.

'Worse, they deliberation you tin return nan supplier for only a short while and support nan weight disconnected permanently afterwards, but each nan investigation shows that this isn't true: group put nan weight backmost connected aft stopping nan drug.'

Another 2022 objective proceedings besides found people taking semaglutide began to regain weight astir 60 weeks aft starting nan medication. 

Writing successful nan journal Nature, researchers said: 'Reductions successful weight... appeared to plateau astir week 60 pinch semaglutide.'

A 2nd 2022 study by researchers astatine nan University of Liverpool besides recovered patients who utilized nan supplier dropped 18 percent of their assemblage weight aft utilizing it for 68 weeks. 

But, aft dropping nan play injections, users would put backmost connected two-thirds of nan weight wrong nan adjacent year.  

As such, experts person warned nan jabs mightiness person to beryllium taken for life because nan fat creeps backmost connected 'the infinitesimal you stop' taking them.  

And nan arena has go truthful communal that forum users are sharing their experiences of hitting nan wall. 

In a Reddit group pinch complete 70,000 members, 1 said: 'I plateau for astir 4 weeks for each 10 to 15 lbs (4.5 to 7 kg) I lose.' 

In a abstracted thread titled 'How do you break a plateau astatine 2.0mg?' a personification said: 'I've been plateauing successful position of weight nonaccomplishment for nan past 3 months astatine 2.0mg [dose]. How tin I break this?'

They added: 'I've been stepping a batch more, started intermittent fasting, and drinking a batch much water, but thing seems to break it.' 

On different thread titled 'seem to person deed a wall', 1 Reddit personification said: 'I've been connected semaglutide for a small complete 6 weeks. I've only mislaid 9 lbs (4kg). 

'I conscionable started nan 0.5mg dose and consciousness for illustration I've deed a wall. I utilized to person small to nary appetite but it's coming backmost and I'm craving definite things again. 

'I'm tense that this isn't moving for me.'

Semaglutide, arsenic good arsenic rival narcotics liraglutide and tirzepatide, have been hailed arsenic monumental breakthroughs successful nan warfare connected obesity.

But a spike successful request for nan jabs, fuelled by personage endorsements, has besides seen world stocks run low. 

Shortages are expected to past until mid-2024 astatine nan earliest.

Oprah Winfrey, Boy George and Sharon Osbourne are among different celebs who person admitted to taking the medication. 

And this week Stephen Fry besides admitted his 'astonishing' weight nonaccomplishment came astatine a price, aft Ozempic caused him to vomit up to 5 times a day.

He said: 'The first week aliases so, I was thinking, "This is astonishing. Not only do I not want to eat, I don't want immoderate intoxicant of immoderate kind. This is going to beryllium brilliant. 

'Then I started emotion sick, and I started getting sicker and sicker and sicker. I was throwing up four, 5 times a time and I thought, "I can't do this". So that's it. The caller variant, Tirzepatide Mounjaro, makes it moreover worse apparently.'

Mounting grounds suggests that successful nan existent world, nan drugs' broadside effects, specified arsenic vomiting and diarrhoea, are proving truthful communal and overwhelming that it makes nan existent versions impractical for astir patients to enactment connected for very long.

The consequence is very precocious diligent drop-out rates successful existent life. 

But there were nary evident precocious drop-out rates among patients utilizing GLP-1 narcotics successful objective trials, which were funded by nan drugs' makers. 

It comes arsenic pharmaceutical titan Novo Nordisk earlier this period besides unveiled promising early results for its experimental supplier amycretin. 

The weight nonaccomplishment pill is akin to Wegovy and Ozempic, by targeting nan aforesaid GLP-1 hormone. 

But it showed patients could suffer much than 13 per cent of their weight aft conscionable 12 weeks — suggesting it could beryllium up to doubly arsenic effective arsenic nan jabs. 

Analysts forecast nan obesity marketplace could beryllium worthy up to £79billion ($100billion) by 2030.

Health experts past month, however, urged Brits not to slope connected weight nonaccomplishment jabs warning they 'are not nan answer' and 'will inevitably origin problems down nan line'.

Ozempic is only available connected the NHS arsenic a curen for managing humor glucose levels successful group pinch type 2 diabetes.

Its melodramatic slimming effects saw doctors and pharmacists crockery it retired 'off-label' for group wanting to lose weight. 

However, wellness chiefs urged against doing truthful because of proviso issues, informing it put diabetics lives astatine risk. 

Wegovy was approved past year, specifically for weight loss. 

A month's proviso is disposable privately successful Boots and Superdrug for astir £200. Eligibility criteria for group wanting nan get nan supplier connected nan NHS is strict.

A deficiency of exercise, mixed pinch unhealthy diets, has been blamed for nan increasing obesity pandemic successful nan UK. 

Latest NHS information shows 26 per cent of adults successful England are obese and a further 38 per cent are overweight but not obese.